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Metabolism
December 5, 2025
5 min

What studying >20,000 patients from the inside taught me about health

This is what changed everything for me...

What studying >20,000 patients from the inside taught me about health

As a nuclear radiologist, I’ve had the privilege of studying more than 20,000 people from the inside through scans: x-ray, ultrasound, CT, MRI, scintigrapy, SPECT/CT and PET/CT.

In the beginning, I mostly looked at things the way I was trained. Abnormality or no abnormality? Is this relevant to the clinical question? If not: describe it, check the box, move on.

But as the years passed, something started to gnaw at me.

I began seeing patterns that didn't fit the story we tell ourselves about health. Scans that were "normal" for the specific diagnostic question, but looked anything but healthy as a whole. Abnormalities we routinely noted as incidental findings because they fell outside the medical framework we could actually do something with at that moment.

One of those kept coming back: fatty liver.

Initially, I took it for granted. That’s how I was trained. Describe it, but don't problematize it. No alcohol? Then it's not an issue.

The first turning point

That changed when I started diving into insulin resistance, visceral fat, and metabolic health about 10 years ago.

Suddenly, the puzzle pieces fell into place. Not just in the literature, but in the scans I saw every single day. Fatty liver turned out to be rarely an isolated finding. It was a marker. A signal that multiple systems had been under pressure for a long time.

That realization brought doubt along with it. Because if this is true, then we are structurally intervening too late.

Modern medicine is exceptionally good at acute care and treating clear-cut disease. But it still often thinks in binaries: sick or not sick. Meanwhile, health behaves like a continuous process. It’s a system that compensates for a long time before it finally fails.

That tension became increasingly clear in my daily work. On PET-CTs, I saw the endgame of disease. But on earlier scans, the first changes were often visible for years without ever leading to a conversation, a plan, or any action.

Why Metaboliq exists

That was the second turning point. Not because I turned "against medicine." On the contrary. But because I realized that both truths exist simultaneously:

  • The medical model works—within its limits.

  • But it largely ignores the phase where the body is already starting to derail.

That is why I'm starting a podcast: Metaboliq. It’s an attempt to build a bridge from the inside out, connecting the established medical order with the growing group of critics who are rightly asking questions about prevention and lifestyle.

The core of that bridge is simple: Health is not a state, but a trainable system.

Between two extremes

A lot of health content chooses one of two sides:

  • Anti-data: "Just listen to your gut"

  • Data without context: Numbers without meaning.

I didn't recognize myself in either. Measuring is valuable, provided you understand what the body is trying to do.

And where many podcasts mainly explain conclusions ("research shows that...") or give advice ("this is what you must do"), Metaboliq wants to do something else: make the medical thought process audible.

That includes uncertainty. It includes doubt. It includes trade-offs.

I don't give answers. I show how I arrive at my answers.

The Metaboliq 3M Framework:

Every episode revolves around the same three questions:

  • The Myth: The mainstream lie or oversimplification we’ve been sold.

  • The Mechanism: The actual physiology and what scientific and clinical data (and scans of course!) really show.

  • The Method: The concrete protocol to train this system in your own life.

No simple fixes. Just learning how to look, think, and weigh options better.

Anyone who has seen thousands of bodies from the inside knows one thing for sure: what we often call "normal" has, in many cases, been dysregulated for years.

Metaboliq is for professionals who recognize that and are willing to look earlier and broader, without betraying their craft. And of course for all of the fellow nerds out there who want to optimize their own health.

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Dr. Andor van den Hoven

Dr. Andor van den Hoven

Nuclear radiologist and longevity expert. Translating frontline science into practical strategies to help you stay vital and healthy. From diagnosis to prevention.

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